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Chuan QIN

Contact:qinchuan@cpl.ac.cn



Academic Experience


2022 - present               Member, Academic Advisory Committee, Chinese Academy of Medical Sciences

2021 - present               Secretary-General, Consortium of Life Sciences Association, China Association for Science and Technology

2020 - present               Director, China National Human Disease Animal Model Resource Center

2018 - present               Chairman, International Association for Comparative Medicine

2018 - present               Chief editor and Reviewer, Animal Models and Experimental Medicine

2017 - present               President, Chinese Association for Laboratory Animal Sciences

2015 - present               Scientific Members, International Council for Laboratory Animal Science

2014 - present               Chief editor and Reviewer, Acta Laboratorium Animalis Scientia Sinica

2008 - present               Chief editor and Reviewer, Chinese Journal of Comparative Medicine

2008 - present               Vice President, Asian Federation of Laboratory Animal Science Associations

2003 - present              Professor, Institute of Laboratory Animal Sciences, PUMC.

2003 - 2022                  Director, Institute of Laboratory Animal Sciences, CAMS.

1994 - 2003                  Associate professor, Institute of Laboratory Animal Sciences, PUMC

1993 - 1994                  Visiting scholar, Department of laboratory animal pathology, University of Tokyo, Japan


Overview of Academic Research


I. Establishment and application of animal models of infectious diseases (e.g. COVID-19, influenza)

II. Comparative medical study in neurodegenerative diseases


Major Honor and Awards


2019       Second place of State Science and Technology Awards, P.R.China

2019       Kirin science and Technology Award - capital excellent science and Technology Innovation Award, Beijing

2018       Science and technology award of Chinese medical association

2018       Science and technology award of Beijing    

2017       The National Award for Excellence in Innovation, P.R.China

2016       Science and Technology Progress Award of Ministry of  Education of China

 

Representative Research Achievements 


1.Wang K#, Jia Z#, Bao L#, Wang L#, Cao L#, Chi H#, Hu Y#, Li Q#, Zhou Y#, Jiang Y, Zhu Q, Deng Y, Liu P, Wang N, Wang L, Liu M, Li Y, Zhu B, Fan K, Fu W, Yang P, Pei X, Cui Z, Qin L, Ge P, Wu J, Liu S, Chen Y, Huang W, Wang Q*, Qin CF*, Wang Y*, Qin C*, Wang X*. Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants. Nature. 2022;603(7903):919-925.


2. Guo Q#, Zhao Y#, Li J#, Liu J#, Yang X#, Guo X, Kuang M, Xia H, Zhang Z, Cao L, Luo Y, Bao L, Wang X, Wei X, Deng W, Wang N, Chen L, Chen J, Zhu H, Gao R, Qin C*, Wang X*, You F*. Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19. Cell Host Microbe. 2021;29(2):222-235.e4.


3. Du S#, Cao Y#, Zhu Q#, Yu P#, Qi F#, Wang G, Du X, Bao L, Deng W, Zhu H, Liu J, Nie J, Zheng Y, Liang H, Liu R, Gong S, Xu H, Yisimayi A, Lv Q, Wang B, He R, Han Y, Zhao W, Bai Y, Qu Y, Gao X, Ji C, Wang Q, Gao N, Huang W, Wang Y, Xie XS*, Su XD*, Xiao J*, Qin C*. Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy. Cell. 2020;183(4):1013-1023.e13.


4. Wang H#, Zhang Y#, Huang B#, Deng W#, Quan Y#, Wang W#, Xu W#, Zhao Y, Li N, Zhang J, Liang H, Bao L, Xu Y, Ding L, Zhou W, Gao H, Liu J, Niu P, Zhao L, Zhen W, Fu H, Yu S, Zhang Z, Xu G, Li C*, Lou Z*, Xu M*, Qin C*, Wu G*, Gao GF*, Tan W*, Yang X*. Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2. Cell. 2020;182(3):713-721.e9.  


5. Deng W#, Bao L#, Liu J#, Xiao C#, Liu J#, Xue J#, Lv Q#, Qi F, Gao H, Yu P, Xu Y, Qu Y, Li F, Xiang Z, Yu H, Gong S, Liu M, Wang G, Wang S, Song Z, Liu Y, Zhao W, Han Y, Zhao L, Liu X, Wei Q, Qin C*. Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques. Science. 2020;369(6505):818-823.


6. Dai L#*, Zheng T#, Xu K#, Han Y#, Xu L#, Huang E, An Y, Cheng Y, Li S, Liu M, Yang M, Li Y, Cheng H, Yuan Y, Zhang W, Ke C, Wong G, Qi J, Qin C*, Yan J*, Gao GF*. A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS. Cell. 2020;182(3):722-733.e11.  


7. Cao Y#, Su B#, Guo X#, Sun W#, Deng Y#, Bao L#, Zhu Q#, Zhang X, Zheng Y, Geng C, Chai X, He R, Li X, Lv Q, Zhu H, Deng W, Xu Y, Wang Y, Qiao L, Tan Y, Song L, Wang G, Du X, Gao N, Liu J, Xiao J, Su XD, Du Z, Feng Y, Qin C*, Qin C*, Jin R*, Xie XS*. Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells. Cell. 2020;182(1):73-84.e16.


8. Gao Q#, Bao L#, Mao H#, Wang L#, Xu K#, Yang M, Li Y, Zhu L, Wang N, Lv Z, Gao H, Ge X, Kan B, Hu Y, Liu J, Cai F, Jiang D, Yin Y, Qin C, Li J, Gong X, Lou X, Shi W, Wu D, Zhang H, Zhu L, Deng W, Li Y, Lu J*, Li C*, Wang X*, Yin W*, Zhang Y*, Qin C*. Development of an inactivated vaccine candidate for SARS-CoV-2. Science. 2020;369(6499):77-81.


9. Bao L#, Deng W#, Huang B#, Gao H#, Liu J#, Ren L, Wei Q, Yu P, Xu Y, Qi F, Qu Y, Li F, Lv Q, Wang W, Xue J, Gong S, Liu M, Wang G, Wang S, Song Z, Zhao L, Liu P, Zhao L, Ye F, Wang H, Zhou W, Zhu N, Zhen W, Yu H, Zhang X, Guo L, Chen L, Wang C, Wang Y, Wang X, Xiao Y, Sun Q, Liu H, Zhu F, Ma C, Yan L, Yang M, Han J, Xu W, Tan W, Peng X, Jin Q, Wu G*, Qin C*. The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice. Nature. 2020;583(7818):830-833.


10. Yang W#, Liu Y, Tu Z, Xiao C, Yan S, Ma X, Guo X, Chen X, Yin P, Yang Z, Yang S, Jiang T, Li S*, Qin C*, Li XJ*. CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys. Cell Res. 2019;29(4):334-336.